Division of Research Spotlight, October 10, 2018
Physicians with The Permanente Medical Group (TPMG) have come up with a novel new way to read ultrasounds, which allows them to correctly identify which ovarian masses are most likely to be cancer.
A study published today in the journal Obstetrics and Gynecology validates an original new process for reading ultrasound scans, developed by Elizabeth (Betty) Suh Burgmann, MD, and TPMG gynecology and radiology physician leaders, which allows them to categorize ovarian masses into different risk groups based on the mass’ size and the presence of blood flow and solid areas.
“In the past, it was difficult to determine the risk of a mass being cancerous, and which women should be recommended to have surgery to remove the mass,” said Dr. Suh-Burgmann, the study’s lead author and regional chair of gynecological oncology for Kaiser Permanente’s Northern California region. “This is the first time that ovarian cancer risk has been systematically assessed among women who have ovarian cysts or masses detected during routine care.”
Ovarian cancer is difficult to treat successfully in its later stages, but outcomes are good when it is found early. With the new radiology guidelines, women at higher risk for ovarian cancer can be promptly referred for surgical evaluation while women at low risk can safely avoid surgery.
The study, “Prospective validation of a standardized ultrasonography-based ovarian cancer risk assessment system,” was based on nearly 44,000 pelvic ultrasounds not related to pregnancy that were done in Kaiser Permanente Northern California in 2016.
The risk of finding an ovarian cancer among the nearly 37,000 women with normal ultrasounds was extremely low: 0.1 percent, or 1 in 1,000.
Among about 7,000 women with abnormal ovarian masses, the new radiology guidelines identified 70 percent of women as having very-low-risk masses (category 1). About 10 percent of women were identified as having higher-risk masses (categories 3 and X).
Women with masses in the low-risk category had an ovarian cancer risk of less than 1 in 500, while women with masses in the high-risk categories had a combined cancer risk of nearly 1 in 5.
“Having a better estimate of risk helps doctors and patients make better choices about whether it makes sense to do surgery to remove the mass, versus monitoring it with repeated ultrasounds,” Dr. Suh-Burgmann said. “We hope that other health care organizations will consider adopting this validated system.”
“A place where doctors can do this.”
“Dr. Suh-Burgmann knew she could help the broad medical community do a better job with ovarian masses, and she doggedly built the partnerships she needed to implement this program, then evaluate it using data from the electronic medical record,” said senior author Lisa J. Herrinton, PhD, research scientist with the Kaiser Permanente Division of Research. “Kaiser Permanente is a place where doctors can do this.”
This story originally appeared in The Division of Research Spotlight